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Original Article
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Korean J Med. 2009;76(1):87-92.
- 유방암 환자에서 동반된 폐동맥 종양 혈전성 미세혈관병증 1예
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유정환, 김용훈, 김대영, 강혜윤, 김인재, 임상욱, 차동훈
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- Pulmonary tumor thrombotic microangiopathy in a patient with breast cancer
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Jeong Hwan Yoo, Yong Hun Kim, Dae Young Kim, Hae Youn Kang, In Jai Kim, Sang Wook Lim, Dong Hoon Cha
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- Abstract
- Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare malignancy-related complication causing severe pulmonary hypertension,
right heart failure, and death. PTTM is characterized by diffuse fibrocellular intimal proliferation and multiple thrombi
formation in the pulmonary arteries and arterioles, which result from invasion of the pulmonary blood vessels by tumor cells.
Establishing the diagnosis of PTTM is very difficult and few cases are diagnosed ante mortem. We report the case of a 48-year-old
woman diagnosed with PTTM before death who developed breast cancer and presented with persistent dyspnea on exertion.
(Korean J Med 76:S87-S92, 2009)
Keywords :Pulmonary tumor thrombotic microangiopathy, Pulmonary hypertension, Breast cancer
