The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;76(1):97-102.
폐농양으로 오인된 베게너 육아종증 1예
김혜옥, 정기환, 김제형, 박형주, 김영식, 신 철
A case of Wegener’s granulomatosis masquerading as a lung abscess
Hye Ok Kim, Ki Hwan Jung, Je Hyeong Kim, Hyung Joo Park, Young-Sik Kim, Chol Shin


Abstract
Wegener’s granulomatosis is a small vessel vasculitis characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tracts and kidney. Early diagnosis and immediate treatment are very important for a better prognosis, but the nonspecific, variable clinical manifestations and radiologic findings make the diagnosis difficult. A positive proteinase 3-antineutrophil cytoplasmic antibody test is helpful for the diagnosis of Wegener’s granulomatosis. Here, we report a case of Wegener’s granulomatosis in 54-year-old man who initially presented with fever and multiple cavitary consolidations on the chest radiograph suggestive of a lung abscess. The final diagnosis of Wegener’s granulomatosis was based on the medical history of otitis media, gradually developed microscopic hematuria, necrotizing granulomatous inflammation on lung histopathology, and a positive proteinase 3-antineutrophil cytoplasmic antibody test. (Korean J Med 76:S97-S102, 2009)

Keywords :Wegener’s granulomatosis, Interstitial lung disease, Antineutrophil cytoplasmic antibody
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