The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;76(1):117-121.
갑상샘 유두암과 동반된 이소성 쿠싱증후군 1예
김용철, 정문경, 송윤미, 권혁상, 정찬권, 문성대, 한제호
A case of ectopic Cushing’s syndrome combined with papillary thyroid carcinoma
Yong Cheol Kim, Mun Kyung Chung, Youn Mi Song, Hyuk Sang Kwon, Chan Kwon Jung, Sung Dae Moon, Je Ho Han


Abstract
Locating a corticotropin-releasing hormone (CRH)- or adrenocorticotropic hormone (ACTH)-secreting tumor is challenging. A 69-year-old woman admitted to our hospital for generalized edema was diagnosed with ectopic Cushing’s syndrome. We attempted to find an ectopic tumor and could establish no ectopic focus except a retropharyngeal mass in the neck. We diagnosed the retropharyngeal mass as thyroid papillary carcinoma and examined whether the thyroid papillary carcinoma was the ectopic focus. No relationship between thyroid papillary carcinoma and ectopic Cushing’s syndrome has been established. We failed to find another ectopic focus, except for the increased uptake of the retropharyngeal mass on fluorodeoxyglucose positron emission tomography (FDG-PET). Ectopic Cushing’s syndrome combined with thyroid papillary carcinoma is very rare, so we report this case along with reviews of related literatures. (Korean J Med 76:S117-S121, 2009)

Keywords :Ectopic CRH, Ectopic ACTH, Thyroid papillary carcinoma
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