The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;76(1):148-153.
비만과 연관된 사구체병증 2예
김민수, 구본승, 오쌍용, 조 현, 정현철, 박종하, 차희정
Two cases of obesity-related glomerulopathy
Min Su Kim, Bon Seung Ku, Ssang Yong Oh, Hyun cho, Hyun Chul Chung, Jongha Park, Hee Jeong Cha


Abstract
Obesity or being overweight may be associated with various functional and structural lesions of the kidneys. It is common in patients with diabetes having a high body mass index (BMI), but it also occurs in patients with increased proteinuria. Recently, we treated a 28-year-old woman and a 15-year-old boy with proteinuria and a high BMI (woman: 35 kg/m2; boy: 27.7 kg/m2). At that time, they were diagnosed with obesity-related glomerulopathy based on the laboratory, urinary, and kidney biopsy findings. After treatment with an angiotensin-converting enzyme inhibitor and weight loss, the proteinuria was sustained in the latter, while it improved in the former. We believe that these cases suggest an association between obesity and glomerulopathy. (Korean J Med 76:S148-S153, 2009)

Keywords :Obesity, Proteinuria, Glomerulosclerosis
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