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Original Article
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Korean J Med. 2009;76(1):169-174.
- 혈액투석 환자의 원발성 위 융모막암종에서 Etoposide와 cisplatin 복합항암 치료 1예
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이지명, 김형욱, 정지한, 심병용, 박우배, 김훈교
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- Partial remission of a primary gastric choriocarcinoma after etoposide and cisplatin chemotherapy in a hemodialysis patient
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Ji Myoung Lee, Hyung Wook Kim, Ji Han Jung, Byoung Yong Shim, Woo Bae Park, Hoon-Kyo Kim
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- Abstract
- Primary gastric choriocarcinomas are rare and no treatment regimen for hemodialysis patients with a primary gastric choriocarcinoma
has been established. We report a partial response to etoposide and cisplatin chemotherapy in a hemodialysis patient with a
primary gastric choriocarcinoma. A 69-year-old woman with end-stage renal disease experienced hematemesis for 3 days.
Gastroduodenoscopy revealed an ulcerative mass with recent bleeding. A subtotal Billroth II gastrectomy was performed and a gastric
choriocarcinoma was identified histopathologically. One month postoperatively, recurrence was diagnosed by detecting an elevated
serum ß-human chorionic gonadotropin (ß-HCG) level and multiple liver and lymph node metastases. The patient was treated
with chemotherapy consisting of etoposide and cisplatin (EP). After six cycles of EP chemotherapy, the tumor size decreased markedly
and a partial response was seen on computed tomography. Post-therapy positron emission tomography showed a complete
metabolic response and the serum ß-HCG level had normalized. (Korean J Med 76:S169-S174, 2009)
Keywords :Choriocarcinoma, Hemodialysis, Etoposide, Cisplatin
