The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;77(2):241-245.
갑상선에서 발생한 소세포암 2예
심성훈, 김희준, 김미정, 차용준, 이윤수, 임규형, 이세훈
Two cases of thyroid small cell carcinoma
Sung Hoon Sim, Hee Jun Kim, Mi-Jung Kim, Yongjun Cha, Yoon Su Lee, Kyu-Hyoung Lim, Se-Hoon Lee


Abstract
Historically, small cell carcinoma in the thyroid has been regarded as a kind of lymphoma and small cell carcinoma in the thyroid as a distinct disease entity is still controversial. Here, we present two cases of thyroid small cell carcinoma that were differentiated from lymphoma, based on immunohistochemical staining. One case was misdiagnosed as anaplastic carcinoma that occurred during the treatment of follicular carcinoma. Both cases responded well to chemotherapy. These cases support the hypothesis that thyroid small cell carcinoma is a distinct disease entity. One should consider small cell carcinoma when there is a rapidly growing mass in the thyroid. (Korean J Med 77:241-245, 2009)

Keywords :Thyroid cancer, Small cell carcinoma
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