The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;77(5):610-615.
미분화 암종이 동반된 췌장의 파골세포 모양 거대세포종양 1예
김금하, 구양서, 김현옥, 김길현, 김건국, 정동해, 김연석
A case of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas
Geum-Ha Kim, Yang Suh Ku, Hyun Ok Kim, Kil Hyun Kim, Koen Kuk Kim, Dong Hae Jung, Yeon Suk Kim


Abstract
An osteoclast-like giant cell tumor of the pancreas is a very rare neoplasm, with only three cases reported in Korea. Due to the rarity of this tumor type, few clinical data are available. We present a case of undifferentiated carcinoma with osteoclast-like giant cell tumor arising in the tail of the pancreas in a 72-year-old woman hospitalized to evaluate epigastric pain and a palpable abdominal mass. Magnetic resonance imaging revealed the presence of a large enhancing mass with septation arising from the tail of the pancreas. A distal pancreatectomy with splenectomy was performed. The pathological diagnosis was undifferentiated carcinoma with osteoclast-like giant cell tumor. Here, we describe the histopathological and immunohistochemical findings and review the clinical features of the cases reported in the Korean literature.

Keywords :Osteoclast-like giant cell tumor, Pancreatic neoplasm, Undifferentiated carcinoma
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