The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;77(1):52-56.
자가면역 간염과 동반된 A형 및 E형 바이러스 중복 간염 1예
권혁진, 우명렬, 박경석, 이상엽, 조현근, 문영명, 조재희
A case of hepatitis A and E coinfection in an autoimmune hepatitis patient
Hyuk Jin Kwon, Myoung Lyeol Woo, Kyung Suk Park, Sang Yeop Yi, Hyeon Geun Cho, Young Myoung Moon, Jae Hee Cho


Abstract
In Korea, the number of Hepatitis A virus (HAV) infections has suddenly increased and has become the most common cause of acute viral hepatitis during recent years. A 36-year-old female was diagnosed with acute fulminant hepatitis caused by HAV. Her clinical symptoms and AST/ALT recovered after supportive treatment; however, a re-elevation of AST/ALT was observed. We performed another viral marker study, autoimmune marker study and liver biopsy to rule out another hepatic insult. As a result, anti-HEV IgM, an anti-nuclear antibody and anti-smooth muscle antibody were positive and liver histology showed chronic hepatitis. In conclusion, we report a case of hepatitis A and E coinfection in an autoimmune hepatitis patient.

Keywords :Autoimmune hepatitis, Hepatitis A, Hepatitis E
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