The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;77(2):390-394.
혈액투석 환자에서 발생한 부갑상선 암종 1예
장세나, 정지한, 신영신, 진동찬, 방병기, 송주용, 김형욱,
A case of parathyroid carcinoma in a dialysis patient
Se Na Jang, Ji-Han Jung, ., Young Shin Shin, Dong Chan Jin, Byung Kee Bang, Joo Yong Song, Hyung Wook Kim


Abstract
A 40-year-old male who had been undergoing dialysis for 21 years was investigated for progressive hypercalcemia in the context of very high intact parathyroid hormone (PTH) levels. Three years earlier, he had developed secondary hyperparathyroidism and had undergone a partial parathyroidectomy. Imaging showed a functional parathyroid gland in the inferior portion of the left thyroid gland. Cervical exploration was performed with a total parathyroidectomy and autotransplantation of the normal gland into the forearm. The histology of the inferior parathyroid gland showed invasive parathyroid carcinoma. Parathyroid carcinoma is rare in the normal population and in hemodialysis patients; only 21 cases involving dialysis patients have been reported. This is the first report in Korea. We review the diagnostic and therapeutic information on the management of parathyroid carcinoma in the setting of hemodialysis.

Keywords :Parathyroid carcinoma, Hemodialysis
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