The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2009;77(2):445-450.
상대정맥 증후군 및 동서맥을 동반한 원발성 심장림프종 1예
장정윤, 이재진, 한재준, 최소영, 맹치훈, 백선경, 곽영태
A case of primary cardiac lymphoma with superior vena cava syndrome and sinus bradycardia
Jeong Yoon Jang, Jae Jin Lee, Jae Joon Han, Soyoung Choi, Chi Hoon Maeng, Sun Kyung Baek, Young-Tae Kwak


Abstract
We report a case of primary cardiac lymphoma (PCL) with superior vena cava syndrome and sinus bradycardia. PCL accounts for 1.3% of primary cardiac tumors. The clinical manifestations of PCL are mainly pericardial effusion, heart failure, and atriculoventricular block. Primary cardiac lymphoma has poor prognosis; therefore, early diagnosis and treatment are recommended for better outcome. We report a case of PCL in a 71-year-old woman who had worsening dyspnea and facial edema. Initial electrocardiography showed sinus bradycardia. Color Doppler imaging and chest computed tomography revealed a large right-atrial mass that extended to the superior and inferior vena cava, with pericardial and pleural effusion. The tumor was partially resected. The pathological diagnosis was diffuse large B-cell lymphoma with expression of CD20. After tumor resection, the patient was treated by systemic chemotherapy with CHOP (cyclosphosphamide, doxorubicin, vincristine, and prednisone) plus rituximab.

Keywords :Lymphoma, Superior vena cava syndrome, Bradycardia
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