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Original Article
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Korean J Med. 2009;77(2):456-459.
- 말기 신부전증 환자에서 Cefepime에 의해 발생한 뇌병증 1예
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안연정, 정용근, 임민희, 배인규, 김선주, 강희영, 허상택
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- A case of Cefepime-induced encephalopathy in a patient with chronic kidney failure
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Yeon Jeong Ahn, Yong Geun Jeong, Min Hee Lim, In Gyu Bae, Sun Joo Kim, Hee Young Kang, Sang Taek Heo
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- Abstract
- Cefepime is a fourth-generation cephalosporin that has been increasingly used in hospitals. Its potential adverse effects, however, have not been thoroughly explored. Unlike the other well-known side effects of cefepime, its neurotoxic effects have rarely been reported. Most neurological side effects associated with antibiotics occur in patients with renal dysfunction. A 67-year-old female with chronic kidney failure was admitted with febrile sense and lower back pain. The patient was treated with cefepime against pyogenic spondylitis and subsequently suffered from deteriorated mental status. Encephalopathy as a side effect resulting from drug treatment was suspected after other possible causes had been ruled out. The antimicrobial prescription was stopped, and the patient’s mental status recovered. In conclusion, the clinical course of the patient improved after immediate withdrawal of cefepime.
Keywords :Cefepime, Chronic kidney failure, Encephalopathy
