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Original Article
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Korean J Med. 2009;77(5):1342-1346.
- Etanercept으로 치료한 류마티스관절염 환자에서 발생한 악성 림프종 1예
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정상경·이주현·이준성·이혜란·장선희·윤보영, , , , ,
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- A case of Etanercept-associated malignant lymphoma in a patient with rheumatoid arthritis
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Sang Kyung Jung, Ju Hyun Lee, June Sung Lee, Hye Ran Lee, Sun Hee Chang, Bo Young Yoon
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- Abstract
- Rheumatoid arthritis (RA) is a chronic inflammatory polyarthritis that is associated with an increased risk of coronary artery disease,
infection, lymphoma, and life expectancy. Several studies have shown that patients with RA have a 2~3x increased risk of developing
lymphomas as compared with the general population. TNF-α antagonist therapy might be independently associated with
an increased risk of lymphoma; however, other studies have shown that the risk of lymphoma is increased in RA patients with severe
disease activity rather than the treatment per se. We experienced a 65-year-old woman who developed Etanercept–associated
malignant lymphoma with rheumatoid arthritis. (Korean J Med 77:S1342-S1346, 2009)
Keywords :Etanercept, Malignant lymphoma, Rheumatoid arthritis
