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Original Article
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Korean J Med. 2010;78(3):316-317.
- Clostridium difficile 관련 설사의 진단
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정두련
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Departments of 1Internal Medicine, 2Radiology and 3Hospital Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea
- Diagnosis of Clostridium difficile-associated diarrhea
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Doo Ryeon Chung
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가톨릭대학교 의과대학 1내과학교실, 2진단방사선과교실, 3병원병리과교실
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- Abstract
- Clostridium difficile-associated diarrhea (CDAD) has been one of common nosocomial infections associated with previous antibiotic use. Early diagnosis and adequate management of CDAD is necessary especially for severe cases, however, diagnosis has not been satisfactory. Cytotoxicity assay or toxigenic culture can be considered as a golden standard for diagnosis of CDAD, however, they are labor intensive and require a long time. Instead, a rapid enzyme immunoassay for toxin A and B has been widely utilized in most clinical laboratories. However, its low sensitivity has also been a limitation. Sigmoidoscopy can be helpful in a rapid diagnosis of CDAD for some cases which show negative results in enzyme immunoassay. (Korean J Med 78:316-317, 2010)
Keywords :Clostridium difficile, Diarrhea, Colitis, Diagnosis, Sigmoidoscopy
