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Original Article
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Korean J Med. 2010;78(3):391-395.
- HIV 환자에서의 특발성 육아종성 간염 1예
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송세빈, 문송미, 조창현, 황연희, 임효석, 손준성, 이미숙
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- A case of idiopathic granulomatous hepatitis in an HIV-infected patient
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Se Bin Song, Song Mi Moon, Chang Hyun Cho, Yeon Hee Hwang, Hyoseok Lim, Jun Seong Son, Mi Suk Lee
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- Abstract
- Patients infected with human immunodeficiency virus (HIV) may develop various liver diseases, including viral hepatitis, granulomatous inflammation, malignancies, vascular disease, drug-induced hepatitis and, sometimes, diseases of unknown origin. In this case, a 35-year-old HIV-infected man presented with fatigue, myalgia, elevated liver enzymes, and multiple skin lesions for 3 months. Since the abdominal computed tomography (CT) and viral marker tests failed to explain the cause of his symptoms and signs, a liver biopsy was performed. This revealed a granuloma consisting of epithelioid cells without necrosis. His symptoms, skin lesions, and abnormal liver enzymes improved without changing his management, including the anti-retroviral agents. He was diagnosed with idiopathic granulomatous hepatitis based on the pathologic findings of the liver and clinical course. Aggressive diagnostic methods, such as a liver biopsy, should be considered for HIV-infected patients with liver disease. (Korean J Med 78:391-395, 2010)
Keywords :Human immunodeficiency virus, Granuloma, Hepatitis
