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Original Article
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Korean J Med. 2010;78(3):396-402.
- 시신경 위축을 동반한 쇼그렌 증후군 1예
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신지혜, 김현숙
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Departments of 1Internal Medicine, 2Radiology and 3Hospital Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea
- A case of optic nerve atrophy in a patient with Sjögren’s syndrome
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Ji-Hae Shin, Hyun-Sook Kim
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가톨릭대학교 의과대학 1내과학교실, 2진단방사선과교실, 3병원병리과교실
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- Abstract
- Sjögren’s syndrome is a chronic inflammatory disorder that is characterized by lymphocytic infiltration of exocrine glands, especially the lacrimal and salivary glands. Although primarily characterized by a particular form of dry eyes (keratoconjunctivitis sicca) and dry mouth (xerostomia), this condition may affect a wide variety of organs and systems, including the skin, lungs, heart, kidneys, and nervous and hematopoietic systems. Optic neuritis is inflammation of the optic nerve and causes loss of vision, usually because of swelling and destruction of the myelin sheath that covers the optic nerve. The most common etiology is multiple sclerosis. Some other causes include infections, tumors, granuloma, autoimmune disorders (e.g., lupus and Sjögren’s syndrome) and the inflammation of vessels (vasculitis) that nourish the optic nerve. In this report, we describe a 16-year-old girl with optic nerve atrophy caused by optic neuritis, which can be a presenting feature of Sjögren’s syndrome. (Korean J Med 78:396-402, 2010)
Keywords :Optic nerve atrophy, Optic neuritis, Sjö, gren’s syndrome
