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Original Article
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Korean J Med. 2010;78(5):564-574.
- B형 간염바이러스 약제 내성의 기전과 치료
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송 병 철
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1Department of Internal Medicine, Dong-A University College of Medicine; 2Division of Nephrology, Busan Medical Center, Busan, Korea
- The mechanism and treatment of anti-viral resistant hepatitis B virus
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Byung-Cheol Song
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1동아대학교 의과대학 내과학교실, 2부산의료원 신장내과
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- Abstract
- Even though substantial advances have been made in the treatment of chronic hepatitis B in the past decade with the use of oral nucleos(t)ide analogues (NAs), emergence of anti-viral resistance is the most important factor in treatment failure for chronic hepatitis B. Therefore, prevention and management of antiviral resistant HBV is major challenge in the era of oral NAs therapy. Recently, several guidelines for the management of antiviral resistant HBV have been published. Herein, I will discuss how to prevent and manage antiviral resistance. (Korean J Med 78:564-574, 2010)
Keywords :Chronic hepatitis B, Antiviral resistance, Nucleos(t)ide analogues, Combination therapy
