The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2010;78(6):766-770.
괴사성 잇몸궤양으로 나타난 말초 T세포 림프종 1예
조홍성, 정유진, 한정연, 김현숙
Departments of 1Internal Medicine and 2Radiation Oncology, Konyang University College of Medicine, Daejeon, Korea
A case of peripheral T-cell lymphoma presenting with a necrotizing gingival ulcer
Hong-Sung Chough, Yu-Jin Jeong, Jung-Yeon Han, Hyun-Sook Kim
건양대학교 의과대학 1내과학교실, 2방사선종양학과


Abstract
Peripheral T-cell lymphoma (PTCL) is a heterogenous group of generally aggressive neoplasms constituting less than 15% of all non-Hodgkin’s lymphomas in adults. PTCL unspecified (PTCL-U) comprises 6% of lymphomas in the United States and Europe. Most patients with PTCL-U present with generalized lymphadenopathy and hemophagocytosis, eosinophilia, and pruritus involving the skin, liver, spleen, and other viscera. Gingival and genital ulcers are a very uncommon manifestation. The diagnosis of PTCL-U is based on the results of a tissue biopsy that shows evidence of T-cell lymphoma that does not meet the criteria for other subtypes of T-cell lymphoma. Here, we describe an 85-year-old man with intermittent fever and necrotizing gingival and genital ulcers who was diagnosed with PTCL-U after a gingival biopsy. (Korean J Med 78:766-770, 2010)

Keywords :Peripheral T-cell lymphoma, Gingival ulcer
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