The Korean Journal of Internal Medicine

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Original Article
Korean J Med. 2011;80(2):319-324.
항응고 치료만으로 호전된 감염 후 파국성 항인지질 증후군 1예
김윤정, 고석찬, 김성두, 이호준, 윤명재, 김수현, 강나리
Catastrophic Antiphospholipid Syndrome Improved by Anticoagulation Alone
Yoon Jeong Kim, Seouk Chan Ko, Sung Du Kim, Ho Jun Lee, Myung Jae Yun, Su Hyun Kim, Na Ree Kang


Abstract
Catastrophic antiphospholipid syndrome (APS) is an accelerated subtype of APS that results in multiorgan failure. Although catastrophic APS represents about 0.8% of all APS cases, it is usually a life-threatening medical condition that requires high clinical awareness. Catastrophic APS has been managed by various therapies, including anticoagulation, corticosteroids, plasma exchange and IV immunoglobulin, but it still has a high mortality rate. A few cases treated by anticoagulation and steroids have been reported in Korea. In this paper, we report a case of catastrophic APS that improved after anticoagulation therapy alone. Thus, we consider hat our case shows another clinical aspect of catastrophic APS.

Keywords :Antiphospholipid syndrome, Pathophysiology, Therapy
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