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Case Report
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Korean J Med. 2014;86(5):637-640. Published online May 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.86.5.637
- 경구용 부데소나이드로 치료한 공통가변성 면역결핍증에서의 설사
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전지현, 임도형, 박창현, 권혁찬, 정지연, 박건우, 이순일
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단국대학교 의과대학 내과학교실
- Effective Treatment of Intractable Diarrhea Associated with Common Variable Immunodeficiency with Oral Budesonide
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Ji Hyun Jeon, Do Hyoung Lim, Chang Hyun Park, Hyeok Chan Kwon, Ji Yeon Jung, Keon Woo Park, Soon Il Lee
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Department of Medicine, Dankook University College of Medicine, Cheonan, Korea
- Corresponding author: Do Hyoung Lim ,Tel: +82-41-550-3294, Fax: +82-41-550-7058, Email: dos143@gmail.com
- Received: July 15, 2013; Revised: August 22, 2013 Accepted: September 9, 2013.
- 공통 가변성 면역결핍증은 가장 흔한 일차성 항체 결핍 증후군의 하나로 많은 환자에서 위장관 증상이 동반된다. 현 재까지 전신 스테로이드 치료가 효과적인 것으로 알려졌으 나 전신 부작용으로 그 사용이 제한적이다. 경구용 부데소나 이드 치료는 전신 부작용 없이 공통 가변성 면역결핍증의 위장관 증상 개선에 효과적인 약물이다.
߽ɾ :공통 가변성 면역결핍증; 설사; 스테로이드
- Abstract
- Common variable immunodeficiency (CVID) is the most common symptomatic primary antibody deficiency syndrome and has a high prevalence of gastrointestinal complications. We report the case of a 36-year-old male with CVID who presented with chronic intractable diarrhea and malabsorption. A comprehensive evaluation revealed no secondary causes of his symptoms. He was treated symptomatically without improvement. After receiving systemic steroid treatment, his symptoms improved, but returned soon after tapering the steroid. When he was subsequently administered oral budesonide, his symptoms and quality of life improved; this effect lasted for 20 months without unacceptable side effects. (Korean J Med 2014;86:637-640)
Keywords :Common variable immunodeficiency, Diarrhea, Steroid
