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Korean J Med. 2014;86(5):647-650. Published online May 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.86.5.647
HIV 감염 환자에서 피부의 좁쌀결핵으로 발현한 IRIS 1예
고재훈, 신범수, 이성수, 임경숙, 이우주, 유정래, 강철인
Immune Reconstitution Inflammatory Syndrome Presenting as Cutaneous Miliary Tuberculosis in an HIV-Infected Patient
Jaehoon Ko, Beomsu Shin, Seong Soo Lee, Kyung-Suk Lim, Woo Joo Lee, Jeong Rae Yoo, Cheol-In Kang
Corresponding author: Cheol-In Kang ,Tel: +82-2-3410-0324, Fax: +82-2-3410-0064, Email: collacin@hotmail.com
Received: May 21, 2013; Revised: August 8, 2013   Accepted: August 22, 2013.
피부의 좁쌀결핵은 면역저하 상태에서 발생하는 결핵의 드문 감염형태로, 구진 농포성 발진과 피부를 포함한 여러 장기로의 결핵균의 혈행성 다장기 감염을 특징으로 한다. 저 자들은 ART를 시작한 HIV 감염 환자에서 피부의 좁쌀결핵 으로 발현한 IRIS 첫 예를 경험하여 이를 보고하는 바이다.

߽ɾ :좁쌀결핵; 피부; 면역재구성염증증후군
Abstract
Tuberculosis is one of the most common opportunistic diseases in human immunodeficiency virus (HIV)-infected patients in Korea, and extra-pulmonary infections are frequent in these patients. Cutaneous miliary tuberculosis is a rare form of tuberculosis that presents as a papulopustular eruption and hematogenous dissemination of Mycobacterium tuberculosis to multiple organs. This has been reported in patients with progressive HIV infection. We report the first case of cutaneous miliary tuberculosis that developed as a manifestation of immune reconstitution inflammatory syndrome (IRIS) after initiating antiretroviral therapy (ART). (Korean J Med 2014;86:647-650)

Keywords :Tuberculosis, Miliary, Skin, Immune reconstitution inflammatory syndrome
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