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Case Report
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Korean J Med. 2014;87(3):379-382. Published online September 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.3.379
- 루푸스 신염 환자에서 항인지질 항체와 연관된 감염 후 대칭적 말초 괴저
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이재성1, 성지석1, 우용문1, 조영준1, 정범진1, 강한나2, 김수정3
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1서울적십자병원 내과
2서울적십자병원 병리과
3서울대학교 의과대학 서울대학교병원 공공보건의료사업단
- Symmetrical Peripheral Gangrene Complicating Escherichia coli Sepsis Associated with Antiphospholipid Antibodies in Lupus Nephritis
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Jae Sung Lee1, Jee Seok Seong1, Yong Moon Woo1, Young Jun Cho1, Beom Jin Jeong1, Han Na Kang2, Su-Jung Kim3
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1Departments of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea
2Departments of Pathology, Seoul Red Cross Hospital, Seoul, Korea
3Division of Public Health Medical Service, Seoul National University Hospital, Seoul University College of Medicine, Seoul, Korea
- Corresponding author: Su-Jung Kim ,Tel: +82-2-2072-0055, Fax: +82-2-2072-0374, Email: annie8012@naver.com
- Received: December 3, 2013; Revised: January 8, 2014 Accepted: March 4, 2014.
- 저자들은 요로감염 패혈증 후 다발성 장기부전을 보인 루푸스 신염 환자에서 항인지질 항체와 연관된 광범위한 대칭적 말초 괴저를 경험하였고 항생제와 고용량 prednisolone, 항응고제 사용으로 호전시킨 1예를 문헌고찰과 함께 보고하는 바이다.
߽ɾ :항인지질 항체; 루푸스 신염; 괴저; 혈전
- Abstract
- Antiphospholipid syndrome (APS) is an autoimmune disease that involves vascular thrombosis and pregnancy morbidity associated with elevated titers of antiphospholipid antibodies. APS can affect any organ and has a variety of clinical manifestations. Infections can be associated with thrombotic events in APS, including the potentially fatal subset catastrophic APS. We report a case of extensive symmetrical peripheral gangrene complicating Escherichia coli sepsis associated with antiphospholipid antibodies in a patient with lupus nephritis.
Keywords :Antibodies, Antiphospholipid, Lupus nephritis, Gangrene, Thrombosis
