-
Case Report
-
Korean J Med. 2014;87(4):491-495. Published online October 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.4.491
- 시프로플록사신 정맥 주사 후 발생한 급성 요세관 괴사와 청력 소실 1예
-
김준재1, 김현정2, 김상현1, 박원도1
-
1인제대학교 의과대학 상계백병원 내과
2인제대학교 의과대학 상계백병원 병리과
- A Case of Acute Tubular Necrosis and Hearing Loss Induced by Intravenous Administration of Ciprofloxacin
-
Jun Jae Kim1, Hyun-Jung Kim2, Sang Hyun Kim1, Won Do Park1
-
1Departments of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
2Departments of Pathology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea
- Corresponding author: Sang Hyun Kim ,Tel: +82-2-950-1353, Fax: +82-2-950-1955, Email: shkim@paik.ac.kr
- Received: February 1, 2013; Revised: March 15, 2013 Accepted: May 23, 2013.
-
߽ɾ :시프로플록사신; 급성신질환; 급성 요세관 괴사; 청력 소실
- Abstract
- Ciprofloxacin is a broad-spectrum antibiotic used to treat a variety of infections. However, acute kidney injury is a rarely reported side effect. Ciprofloxacin-related nephrotoxicity typically manifests as acute tubulointerstitial nephritis. To the best of our knowledge, few cases of acute tubular necrosis as a complication of ciprofloxacin have been reported to date. We herein describe a case involving a 41-year-old woman treated with intravenous ciprofloxacin at 200 mg twice daily for gastroenteritis. One day after initiation of treatment, her serum creatinine level increased from 0.95 to 3.83 mg/dL and she experienced impaired hearing. Five days later, renal biopsy demonstrated acute tubular necrosis. The acute tubular necrosis encountered in this patient resolved; however, short-term hemodialysis was required. This is the first reported case of acute kidney injury associated with ciprofloxacin use in Korea.
Keywords :Ciprofloxacin, Acute kidney injury, Acute tubular necrosis, Hearing loss
