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Case Report
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Korean J Med. 2014;87(5):603-608. Published online November 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.5.603
- 다발·양측성 신세포암이 발병한 폰히펠린다우병 환자의 고주파 절제술
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문상이, 김동현, 정의한, 박소영, 박미경, 김덕규, 서성환
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동아대학교 의과대학 내과학교실
- Case of Successful Radiofrequency Ablation of Multiple Bilateral Renal Cell Carcinomas in von Hippel-Lindau Disease
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Sang Yi Moon, Dong Hyun Kim, Eui Han Jung, So Young Park, Mi Kyung Park, Duk Kyu Kim, Sunghwan Suh
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Departments of Internal Medicine, College of Medicine, Dong-A University, Busan, Korea
- Corresponding author: Sunghwan Suh ,Tel: +82-51-240-2747, Fax: +82-51-240-5852, Email: suhs@dau.ac.kr
- Received: October 19, 2013; Revised: February 19, 2014 Accepted: March 11, 2014.
- 폰히펠-린다우병의 신세포암의 표준치료는 콩팥 단위 보존 수술이지만 다발성, 양측성 및 재발을 잘한다는 특성으로 인해 여러 가지 한계가 존재하여, 최근에는 고주파 절제술을 통한 신세포암의 치료가 소개되고 있다. 저자들은 폰히펠-린다우병 환자가 다발성, 양측성 신세포암을 진단 후 순차적인 고주파 절제술을 통한 성공적인 치료의 1예를 문헌고찰과 함께 보고하고자 한다.
߽ɾ :폰히펠-린다우병; 신세포암; 카테터 절제술
- Abstract
- Von Hippel-Lindau (VHL) disease is an inherited, autosomal dominant syndrome that manifests as a variety of benign and malignant tumors in various organs. Notably, renal cell carcinoma (RCC) in patients with VHL disease tends to be multifocal and bilateral, and tends to recur or new tumors develop after removal. Radiofrequency ablation (RFA) has recently been introduced as a minimally invasive treatment for small hereditary RCCs with a low complication rate and a minimal decrease in renal function. We present a case of successful RFA of multiple bilateral RCCs in a 24-year-old female with VHL. Computed tomography (CT) of the abdomen revealed multiple bilateral RCCs. The patient received sequential RFA for the bilateral RCCs, resulting in a complete response. At the time of writing, there was no sign of recurrence or renal failure. In conclusion, percutaneous RFA is a promising treatment for VHL patients who cannot undergo surgery, with excellent treatment outcomes and minimal change in renal function.
Keywords :von Hippel Lindau Disease, Renal cell carcinoma, Ablation
