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Case Report
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Korean J Med. 2014;87(5):625-629. Published online November 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.5.625
- 미만성 거대B세포 항암치료 중 유발된 주기적 저칼륨성 마비 1예
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하경선, 박영재, 박성수, 이준엽, 김지현, 장인애, 변재호
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가톨릭대학교 의과대학 내과학교실
- Glucocorticoid Triggers an Attack of Periodic Hypokalemic Paralysis during Treatment for Diffuse Large B-cell Lymphoma
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Kyung Sun Ha, Young Jae Park, Sung Soo Park, Joon Yub Lee, Ji Hyun Kim, Inae Jang, Jae Ho Byun
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Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
- Corresponding author: Jae Ho Byun ,Tel: +82-32-280-5857, Fax: +82-32-280-5987, Email: jhbyun37@catholic.ac.kr
- Received: November 20, 2013; Revised: February 24, 2014 Accepted: March 29, 2014.
- 이번 증례는 드문 예지만 항암치료를 위해 투여한 스테로이드가 주기적 저칼륨성 마비의 유발 인자로 작용할 수 있음을 보여준다. 미만성 거대B세포 림프종의 치료 중 주기적 저칼륨성 마비가 있는 경우 칼륨 수치에 대한 측정과 칼륨보충이 필요하다.
߽ɾ :저칼륨성 마비; 미만성 거대B세포 림프종
- Abstract
- Hypokalemic periodic paralysis is a rare disorder characterized by sudden onset of weakness and low serum potassium levels. We report a case provoked by combination chemotherapy including prednisolone. A 23-yr-man, diagnosed with diffuse large B-cell lymphoma, received chemotherapy. He developed significant weakness in upper and lower extremities during chemotherapy, and his serum potassium level was 1.7 mmol/L. Potassium replacement restored the weakness. Further workup revealed that prednisolone had provoked hypokalemic paralysis. As prednisolone triggered an attack of hypokalemic periodic paralysis, it should be administered with caution, particularly in patients with periodic paralysis.
Keywords :Hypokalemic periodic paralysis, Diffuse large B-cell lymphoma
