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Original Article
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Korean J Med. 2014;87(6):698-704. Published online December 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.87.6.698
- ABO 혈액형 부적합 신장이식 환자에서 혈연 간 신장이식과 비혈연 간 신장이식의 성적 비교
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박우영1,3, 한승엽1,3, 황은아1,3, 박성배1,3, 박의준2,3, 김형태2,3, 조원현2,3
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1계명대학교 의과대학 내과학교실
2계명대학교 의과대학 외과학교실
3계명대학교 신장연구소
- Clinical Outcomes between Living Related and Living Unrelated Kidney Transplantation in ABO-Incompatible Kidney Transplant Recipients
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Wooyeong Park1,3, Seungyeup Han1,3, Eunah Hwang1,3, Sungbae Park1,3, Uijun Park2,3, Hyungtae Kim2,3, Wonhyun Cho2,3
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1Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea
2Department of Surgery, Keimyung University School of Medicine, Daegu, Korea
3Keimyung Kidney Institute, Daegu, Korea
- Corresponding author: Seungyeup Han ,Tel: +82-53-250-7399, Fax: +82-53-253-7976, Email: hansy@dsmc.or.kr
- Received: April 13, 2014; Revised: May 1, 2014 Accepted: May 15, 2014.
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- Abstract
- Background/Aims
Kidney transplantation (KT) is the best treatment for end-stage renal disease patients. Although previous studies have demonstrated that the clinical outcome following living related (LR) KT is better than that following unrelated (LUR) KT in ABO-compatible KT recipients, recent studies showed no differences in clinical outcomes between the two treatments. In this study, we compared the clinical outcomes of LR and LUR KT in ABO-incompatible KT recipients. Methods: From January 2011 to August 2013, 19 cases of ABO-incompatible KT were analyzed retrospectively. Eight kidneys (7 cases of parent-offspring and 1 case of siblings, Group 1) were donated from living-related donors and 11 (all spousal donors, Group 2) from living-unrelated donors. We investigated patient survival, graft survival, acute rejection, graft function, and complications. Results: On Kaplan-Meier analysis, patient and graft survival during follow-up were 87.5% and 87.5% in Group 1; both were 100% in Group 2. Acute rejection, graft function, and medical and surgical complications were not significantly different between the two groups. Conclusions: The short-term clinical outcomes between LR and LUR KT in ABO-incompatible KT recipients were equivalent. Most domestic cases of LUR KT are from spousal donors and the spousal donor will be a major donor in ABO-incompatible KT patients.
Keywords :Kidney transplantation, Living-unrelated, ABO-incompatible
