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Special Review
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Korean J Med. 2015;88(1):1-8. Published online January 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.1.1
- 전통적 완하제
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이봉은1, 이태희2, 김성은3, 박경식4, 박선영5, 신정은6, 정기욱7, 최석채8, 홍경섭9, 홍성노10, 대한소화기기능성질환ㆍ운동학회 변비 및 항문직장기능 연구회
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1부산대학교 의과대학 내과학교실
2순천향대학교 의과대학 소화기연구소
3이화여자대학교 의학전문대학원 내과학교실
4계명대학교 의과대학 내과학교실
5전남대학교 의과대학 내과학교실
6단국대학교 의과대학 내과학교실
7울산대학교 의과대학 소화기내과학교실
8원광대학교 의과대학 내과학교실 및 소화기질환 연구소
9서울대학교 의과대학 내과학교실
10성균관대학교 의과대학 내과학교실
- Conventional Laxatives
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Bong Eun Lee1, Tae Hee Lee2, Seong-Eun Kim3, Kyung Sik Park4, Seon-Young Park5, Jeong Eun Shin6, Kee Wook Jung7, Suck Chei Choi8, Kyoung Sup Hong9, Sung Noh Hong10, Constipation Research Group of the Korean Society of Neurogastroenterology and Motility
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1Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
2Institute for Digestive Research, Soonchunhyang University College of Medicine, Seoul, Korea
3Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea
4Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea
5Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
6Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea
7Department of Gastroenterology, University of Ulsan College of Medicine, Seoul, Korea
8Department of Internal Medicine and Digestive Disease Research Institute, Wonkwang University School of Medicine, Iksan, Korea
9Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
10Department of Internal Medicine, Sungkyunwan University School of Medicine, Seoul, Korea
- Corresponding author: Tae Hee Lee ,Tel: +82-2-709-9691, Fax: +82-2-709-9696, Email: iman0825@naver.com
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- Abstract
- Based on published guidelines on the management of chronic constipation, secondary causes should be excluded and then patients should be told to increase their dietary fiber intake to 20-25 g per day. If these measures do not improve the symptoms, conventional laxatives are generally the next choice. Although there is limited evidence for the efficacy of these older laxatives due to a lack of well-designed clinical trials, most clinicians agree that they are effective at relieving the symptoms of constipation. Conventional laxatives include bulk-forming, osmotic, and stimulant laxatives. Bulking laxatives consist of fiber such as psyllium, cellulose, and bran. Osmotic laxatives are classified into sugar-based laxatives and polyethylene glycol. Bisacodyl and sodium picosulfate are stimulant laxatives. Understanding their mechanisms of action, efficacy, and side effects might improve the quality of life of patients suffering from chronic constipation.
Keywords :Constipation, Laxatives
