The Korean Journal of Internal Medicine

Special Review: Korean J Med. 2015;88(2):127-134. Published online February 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.2.127; 좌심실 수축 기능 저하 심부전증의 치료; 박진주^1,2, 최동주^1,2,3; ¹서울대학교 의과대학 분당서울대학교병원 심장혈관센터
²서울대학교 의과대학 분당서울대학교병원 내과
³서울대학교 의과대학 내과학교실; Treatment of Heart Failure with Reduced Ejection Fraction: Current Update; Jin Joo Park^1,2, Dong-Ju Choi^1,2,3; ¹Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea
²Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
³Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; Corresponding author: Dong-Ju Choi ,Tel: +82-31-787-7007, Fax: +82-31-787-4290, Email: djchoi@snu.ac.kr

Abstract: The prevalence of heart failure (HF) has been steadily increasing and it now creates an enormous social and economic burden. HF is a syndrome characterized by a high mortality rate, frequent hospitalization, a reduced quality of life, and a complex therapeutic regimen. In the last three decades, major progress in both the diagnosis and management of HF has taken place, and the pharmacologic and non-pharmacologic advances have led to a significant improvement in survival and symptoms in HF patients. After an accurate diagnosis, a proper HF management plan requires a multi-level team approach comprised of the correct combination of drug therapy, device therapy, and surgery, including heart transplantation. In this review, we focused on the pharmacologic and non-pharmacologic treatment strategies for HF with reduced ejection fraction. The goal was to develop treatment guidelines based on significant evidence derived from large clinical trials.

Keywords :Systolic heart failure, Practice guideline