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Case Report
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Korean J Med. 2015;88(2):207-211. Published online February 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.2.207
- 고칼슘혈증 동반 사르코이드증에서 정상 혈중 비타민 D를 보인 증례
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전재한1, 서정범1, 황인량1, 박혜윤1, 김정식2, 박근규1, 김정국1
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1경북대학교 의학전문대학원 내과학교실
2경북대학교 의학전문대학원 병리과학교실
- Case of Sarcoidosis-Related Hypercalcemia with Normal Serum 1,25(OH)2D
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Jae-Han Jeon1, Jung-Bum Seo1, In-Ryang Hwang1, Hye-Yoon Park1, Jeong-Shik Kim2, Keun-Gyu Park1, Jung-Guk Kim1
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1Departments of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea
2Departments of Pathology, Kyungpook National University School of Medicine, Daegu, Korea
- Corresponding author: Jung-Guk Kim ,Tel: +82-53-200-5566, Fax: +82-53-426-6722, Email: jugkim@knu.ac.kr
- Received: November 22, 2013; Revised: January 7, 2014 Accepted: July 11, 2014.
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߽ɾ :고칼슘혈증; 사르코이드증; 비타민 D
- Abstract
- Diagnosing hypercalcemia is often challenging because a wide spectrum of diseases-such as malignancy, granulomatous disease, and primary hyperparathyroidism-should be considered. Sarcoidosis is a rare cause of hypercalcemia. The case of a 77-year-old male presenting with sarcoidosis-associated hypercalcemia whose serum 1,25(OH)2D level was normal is reported here. Despite a normal 1,25(OH)2D level and minimally enlarged hilar lymphadenopathy, the serum angiotensin-converting enzyme (ACE) level was increased. Mediastinoscopic biopsy of the right lower paratracheal lymph node revealed pathological findings compatible with sarcoidosis. Treatment with 30 mg/day oral prednisone was started. Currently, the patient is being treated with a tapered dose of oral prednisone and small doses of vitamin D and calcium. Despite its low incidence, sarcoidosis should be considered a cause of hypercalcemia. The important diagnostic factors are not only serum calcitriol levels but also serum ACE levels and pathological findings.
Keywords :Hypercalcemia, Sarcoidosis, Vitamin D
