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Case Report
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Korean J Med. 2015;88(2):236-240. Published online February 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.2.236
- HIV 감염인에서 발생한 골다공증성 골절: 증례보고 및 문헌고찰
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정연오, 장동원, 권용환, 김석원, 박수연, 진범식, 신형식
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국립중앙의료원 감염병센터
- HIV-Infected Patients with Osteoporotic Fractures: A Case Report and Review of the Literature
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Yeon Oh Jeong, Dong Won Jang, Yong Hwan Kwon, Seok Weon Kim, Soo Yeon Park, Bum Sik Chin, Hyoung-Shik Shin
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Center for Infectious Diseases, National Medical Center, Seoul, Korea
- Corresponding author: Hyoung-Shik Shin ,Tel: +82-2-2260-7114, Fax: +82-2-2262-4749, Email: hyoungsshin@gmail.com
- Received: February 5, 2014; Revised: March 10, 2014 Accepted: June 16, 2014.
- 항레트로바이러스 치료제의 발달로 HIV 감염인의 수명이 획기적으로 연장되면서 비에이즈(non-acquired immune deficiency syndrome) 관련 질환인 심혈관 질환, 암, 골다공증성 골절 등의 합병증도 증가했다. 특히 HIV 감염인은 비감염인에 비해 골다공증 유병률이 약 3배 정도 높고 골절은 약 2배 정도 높다. 고령의 HIV 감염인이 많아지면서 조기에 골다공증을 진단하고 치료하기 위한 BMD 검사가 중요하게 되었다. 본 연구에서는 국내 HIV 감염인에서 발생한 골다공증성 골절 6예를 경험했기에 이를 문헌고찰과 함께 보고하는 바이다.
߽ɾ :인체면역결핍 바이러스; 골다공증; 골절
- Abstract
- The average life expectancy of human immunodeficiency virus (HIV)-infected patients has improved dramatically following the advent of highly active anti-retroviral therapy. However, this increased life expectancy has led to a greater incidence of non-acquired immune deficiency syndrome related diseases, including cardiovascular diseases and other malignancies. Increased bone fragility is also a significant concern, with the incidence of osteoporosis and osteoporotic fractures 3- and 2-times more likely, respectively, among HIV-infected patients. Bone mineral density screenings for osteoporosis will therefore become more important as the HIV-infected population ages. Here, we describe six cases of osteoporotic fractures in HIV-infected patients in Korea.
Keywords :Human immunodeficiency virus (HIV), Osteoporosis, Fracture
