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Case Report
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Korean J Med. 2015;88(3):350-355. Published online March 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.3.350
- 전신경화증과 류마티스 관절염의 중복 증후군 3예
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이슬기, 유쾌한, 이걸, 김인영, 권희진, 정혜민, 고은미
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성균관대학교 의과대학 삼성서울병원 내과
- Three Cases of Overlap Syndrome Consisting of Systemic Sclerosis and Rheumatoid Arthritis
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Seulkee Lee, Kwai Han Yoo, Keol Lee, In Young Kim, Hee Jin Kwon, Hyemin Jeong, Eun-Mi Koh
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Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
- Corresponding author: Eun-Mi Koh ,Tel: +82-2-3410-3433, Fax: +82-2-3410-3849, Email: emkoh@skku.edu
- Received: June 4, 2014; Revised: July 21, 2014 Accepted: September 3, 2014.
- 저자들은 전신경화증을 가지고 있던 환자 중 다발성 관절염으로 내원해 류마티스 관절염과의 중복 증후군으로 진단된 환자 3예를 경험했기에 문헌고찰과 함께 보고하는 바이다.
߽ɾ :전신경화증; 류마티스 관절염
- Abstract
- Overlap syndrome is defined as a disease entity that fulfills the classification criteria of at least two different rheumatologic diseases simultaneously. Overlap of systemic sclerosis (SSc) and rheumatoid arthritis (RA) is less common than the overlap of polymyositis with SSc or systemic lupus erythematosus. Distinguishing RA from SSc can be difficult because arthralgia is a frequent symptom of both. We observed three cases of RA and SSc overlap. In each case, RA occurred in sequence with SSc, with a period of 4-15 years between the onset of each disease. In one case, the patient had diffuse SSc, which is rare among overlap syndrome patients. Previously, only one case of overlap syndrome involving SSc and RA has been reported in Korea; herein, we report our cases with a review of the literature.
Keywords :Systemic sclerosis, Rheumatoid arthritis
