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Case Report
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Korean J Med. 2025;100(6):309-314. Published online December 1, 2025.
DOI: https://doi.org/10.3904/kjm.2025.100.6.309
- 무증상 대장궤양으로 발현된 단형성 상피친화성 장 T-세포 림프종 1예
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박계원, 김은선, 최혁순, 이재민, 진윤태, 전훈재, 금보라
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고려대학교 의과대학 고려대학교안암병원 소화기내과
- A Lethal Case of Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma Presented as Asymptomatic Colonic Ulcer
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Gyewon Park, Eun Sun Kim, Hyuk Soon Choi, Jae Min Lee, Yoon Tae Jeen, Hoon Jai Chun, Bora Keum
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Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea
- Corresponding author: Bora Keum ,Tel: +82-2-920-6555, Fax: +82-2-953-1943, Email: borakeum@hanmail.net
- Received: October 24, 2024; Revised: December 13, 2024 Accepted: January 20, 2025.
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߽ɾ :림프종; 장병증 연관 T세포 림프종; T세포 림프종
- Abstract
- Intestinal T-cell lymphoma is an uncommon type of non-Hodgkin lymphoma that primarily affects the gastrointestinal tract. Among the known subtypes, monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a particularly aggressive form characterized by poor prognosis and high mortality. Its rarity and diverse clinical presentations hinder clinical research and the establishment of standardized treatment protocols. Additionally, the treatment response and overall survival rates are typically very low. Herein, we report the case of a 70-year-old man who was referred for evaluation of an asymptomatic colonic ulcer that could not be diagnosed by colonoscopic biopsy but was finally identified as MEITL following surgical resection. Although the patient was diagnosed relatively early during clinical evaluation, treatment initiation was delayed owing to intestinal perforation. Several clinical findings should be considered when diagnosing MEITL. First, early diagnosis is necessary for prompt treatment. Second, gastrointestinal lymphoma should be suspected in patients with atypical or unexplained gastrointestinal findings. When endoscopic biopsy is feasible, like in this case, careful sampling is essential. Lastly, even with early diagnosed, prompt therapeutic intervention is crucial, as MEITL can progress rapidly.
Keywords :Lymphoma, Enteropathy-associated T-cell lymphoma, T-cell lymphoma
