Korean J Med > Volume 78(4); 2010 > Article
The Korean Journal of Medicine 2010;78(4):499-502.
A case of infective endocarditis with endophthalmitis and septic arthritis caused by pneumococcal bacteremia
Joo Hui Kim, Jung Min Jo, Mi Seon Shin, Min Jung Kim, You Jin Chang, Hyun Lim, Chang Min Choi
폐렴구균 균혈증에 의한 세균성 심내막염, 안구내염 및 화농성 관절염 1예
김주희, 조정민, 신미선, 김민정, 장유진, 임 현, 최창민
Abstract
Pneumococcal endocarditis accompanied by pneumococcal bacteremia is a rare condition. However, its clinical course is typically aggressive and associated with high morbidity and mortality rates. We report a case of a 67-year-old male who had small cell lung cancer and was undergoing concurrent chemoradiation therapy, and who presented with pneumococcal bacteremia complicated by infective endocarditis, endogenous endophthalmitis, and septic arthritis of the wrist. He presented with fever, sudden blindness, and a systolic cardiac murmur. Blood cultures were positive for penicillin susceptible Streptococcus pneumoniae. Despite appropriate treatment with intravenous and intravitreal antibiotics, destructive changes still appeared in his vitreous, mitral, and aortic valves. He underwent a vitrectomy and mitral and aortic valve replacement. We were able to prevent further embolic events with antibiotics and early surgical management.
Key Words: Streptococcus pneumoniae; Endocarditis; Endophthalmitis; Infectious arthritis


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