Korean J Med > Volume 78(3); 2010 > Article
The Korean Journal of Medicine 2010;78(3):375-380.
A case of adult nesidioblastosis mimicking an insulinoma and autoimmune hypoglycemia
Yenna Lee, Minjoo Kim, Tae Hyuk Kim, Jung Ah Lim, Su-Jung Kim, Haeryoung Kim, Sung Hee Choi
인슐린종과 자가면역성 저혈당을 모방한 성인 랑게르한스 섬모세포 증식증 1예
이예나, 김민주, 김태혁, 임정아, 김수정, 김혜령, 최성희
Abstract
Hyperinsulinemic hypoglycemia in the absence of exogenous insulin use is caused by disorders such as insulinoma, diffuse β-cell hyperplasia/nesidioblastosis, and autoimmune hypoglycemia. Nesidioblastosis is a rare cause of hypoglycemia in adults, accounting for 0.5~7.0% of organic hyperinsulinemia cases. Although pancreatic resection is considered the best treatment modality for curing nesidioblastosis, there is no consensus regarding the indications for and extent of the surgery due to its high risk and complication rate. A 75-year-old woman presented with an altered mental state, a mass suspected of being an insulinoma, and insulin receptor antibodies. The patient underwent surgery because of recurrent life-threatening hypoglycemia. Postoperative pathology of her pancreas revealed nesidioblastosis. (Korean J Med 78:375-380, 2010)
Key Words: Nesidioblastosis; Insulinoma; Insulin receptor antibody; Hyperinsulinemia; Hypoglycemia


TOOLS
METRICS Graph View
  • 1,562 View
  • 16 Download

Editorial Office
101-2501, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-2271-6791    Fax: +82-2-790-0993    E-mail: kaim@kams.or.kr                

Copyright © 2025 by The Korean Association of Internal Medicine.

Developed in M2PI

Close layer
prev next