A case of adult nesidioblastosis mimicking an insulinoma and autoimmune hypoglycemia |
Yenna Lee, Minjoo Kim, Tae Hyuk Kim, Jung Ah Lim, Su-Jung Kim, Haeryoung Kim, Sung Hee Choi |
|
인슐린종과 자가면역성 저혈당을 모방한 성인 랑게르한스 섬모세포 증식증 1예 |
이예나, 김민주, 김태혁, 임정아, 김수정, 김혜령, 최성희 |
|
|
|
Abstract |
Hyperinsulinemic hypoglycemia in the absence of exogenous insulin use is caused by disorders such as insulinoma, diffuse β-cell hyperplasia/nesidioblastosis, and autoimmune hypoglycemia. Nesidioblastosis is a rare cause of hypoglycemia in adults, accounting for 0.5~7.0% of organic hyperinsulinemia cases. Although pancreatic resection is considered the best treatment modality for curing nesidioblastosis, there is no consensus regarding the indications for and extent of the surgery due to its high risk and complication rate. A 75-year-old woman presented with an altered mental state, a mass suspected of being an insulinoma, and insulin receptor antibodies. The patient underwent surgery because of recurrent life-threatening hypoglycemia. Postoperative pathology of her pancreas revealed nesidioblastosis. (Korean J Med 78:375-380, 2010) |
Key Words:
Nesidioblastosis; Insulinoma; Insulin receptor antibody; Hyperinsulinemia; Hypoglycemia |
|